Jean-Michel Weber – Publications

• Lactate signaling for fuel selection in rainbow trout: Mobilization of energy reserves.
  Talarico GGM, Thoral E, Farhat E, Teulier L, Mennigen J and Weber J-M.
  Am. J. Physiol. 2023.
  
  
• The mammalian insulin antagonist S961 does not exhibit insulin receptor antagonism in rainbow trout in vivo.
  Talarico GGM, Grégoire M, Weber J-M and Mennigen J. J. Fish Biol. 2023.
  
  
• Are we any closer to understanding why fish can die after severe exercise?
  Holder PE, Wood CM, Lawrence MJ, Clark TD, Suski CD, Weber J-M, Danylchuk AJ and Cooke SJ. Fish and Fisheries 2022.
  
  
• Epigenetic and post-transcriptional repression support metabolic suppression in chronically hypoxic goldfish.
  Farhat E, Talarico GGM, Gregoire M, Weber J-M and Mennigen JA. Scientific Reports 2022.
  
  
• Different patterns of chronic hypoxia lead to hierarchical adaptative mechanisms in goldfish metabolism. 
  Thoral E, Farhat E, Roussel D, Cheng H, Guillard L, Pamenter ME, Weber J-M and Teulier L. J. Exp. Biol. 2022.
  
  
• Na⁺/K⁺-ATPase activity is regionally regulated by acute hypoxia in naked mole-rat brain.
  Farhat E, Devereaux MME, Cheng H, Weber J-M and Pamenter ME. Neuroscience Letters 2021.
  
  
• Hypometabolic responses to chronic hypoxia: A potential role for membrane lipids.
  Farhat E and Weber J-M. Metabolites 2021.
  
  
• Alanine alters carbohydrate metabolism in rainbow trout: glucose flux and cell signaling.
  Jubouri M, Talarico GGM, Weber J-M and Mennigen JA. J. Exp. Biol. 2021.

• Goldfish response to chronic hypoxia: Mitochondrial respiration, fuel preference and energy metabolism.
  Farhat E, Cheng H, Romestaing C, Pamenter M and Weber J-M. Metabolites 2021.
  
  
• Naked mole-rats suppress energy metabolism and modulate membrane cholesterol in chronic hypoxia.
  Farhat E, Devereaux M, Pamenter M and Weber J-M. Am. J. Physiol. 2020.
  
  
• Unexpected effect of insulin on glucose disposal explains glucose intolerance of rainbow trout.
  Forbes JLI, Kostyniuk DJ, Mennigen JA and Weber J-M. Am. J. Physiol. 2019.
  
  
• Glucagon regulation of carbohydrate metabolism in rainbow trout: in vivo glucose fluxes and gene expression.
  Forbes JLI, Kostyniuk DJ, Mennigen JA and Weber J-M. J. Exp. Biol. 2019.
  
  
• Hypoxia-induced remodelling of goldfish membranes.
  Farhat E, Turenne ED, Choi K and Weber J-M. Comp. Biochem. Physiol. B. 2019.
  
  
• Lean, mean, lipolytic machines: Lipid mobilization in rainbow trout during graded swimming.
  Turenne ED and Weber J-M. J. Exp. Biol. 2018.
  
  
• Diversity in membrane composition is associated with variation in thermoregulatory capacity in hymenopterans.
  Rodriguez E, Weber J-M and Darveau C-A. Comp. Biochem. Physiol. B. 2018.
  
  
• Metabolic fuel kinetics in fish: swimming, hypoxia and muscle membranes.
  Weber J-M, Choi K, Gonzalez A, and Omlin T. J. Exp. Biol. 2016.
  
  
• Proline as a fuel for insect flight: enhancing carbohydrate oxidation in hymenopterans.
  Teulier L, Weber J-M, Crevier J and Darveau C-A.  Proc. R. Soc. B. 2016.
  
  
• Revealing how goldfish defy anoxia.
  Weber J-M. J. Exp. Biol. 2016.
  
  
• Gemfibrozil disrupts the metabolism of circulating lipids in bobwhite quails.
  Bussière-Côté S, Omlin T, de Càssia Pinheiro E and Weber J-M. Comp. Biochem. Physiol. C 2016.
  
  
• Coping with an exogenous glucose overload: Glucose kinetics of rainbow trout during graded swimming.  
  Choi K and Weber J-M.  Am. J. Physiol. 2016.
  
  
• Pushing the limits of glucose kinetics: How rainbow trout cope with a carbohydrate overload. 
  Choi K and Weber J-M.  J. Exp. Biol. 2015.
  
  
• Fuel metabolism in Canada geese: effects of glucagon on glucose kinetics. 
  Vaillancourt E and Weber J-M. Am. J. Physiol. 2015.
  
  
• Membranes as a possible pacemaker of metabolism in cypriniform fish: does phylogeny matter?
  Gonzalez A, Pagé B and Weber J-M. J. Exp. Biol. 2015.
  
  
• Setting the pace of life: Membrane composition of flight muscle varies with metabolic rate of hovering orchid bees.
  Rodriguez E, Weber J-M, Pagé B, Roubik DW, Suarez RK and Darveau C-A. Proc. R. Soc. B. 2015.
  
  
• Exogenous lactate supply affects lactate kinetics of rainbow trout, not swimming performance.
  Omlin T, Langevin K and Weber J-M. Am. J. Physiol. 2014.
  
  
• Lactate kinetics of rainbow trout during graded exercise: Do catheters affect the cost of transport ?
  Teulier L, Omlin T and Weber J-M.  J. Exp. Biol. 2013.
  
  
• PCB-153 and temperature cause restructuring of goldfish membranes: homeoviscous response to a chemical fluidiser.
  Gonzalez A, Odjélé A and Weber J-M. Aquat. Toxicol. 2013.
  
  
• Exhausting exercise and tissue-specific expression of monocarboxylate transporters in rainbow trout.
  Omlin T and Weber J-M.  Am. J. Physiol. 2013.
  
  
• Extending food deprivation reverses the short-term lipolytic response to fasting: Role of the triacylglycerol/fatty acid cycle. 
  Weber J-M and Reidy SP.  J. Exp. Biol. 2012.
  
  
• Determining seabird body condition using nonlethal measures.
  Jacobs SR, Elliott K, Guigueno MF, Gaston AJ, Redman P, Speakman JR and Weber J-M. Physiol. Biochem. Zool. 2012.
  
  
• The fibrate drug Gemfibrozil disrupts lipoprotein metabolism in rainbow trout.
  Prindiville JS, Mennigen JA, Zamora JM, Moon TW, and Weber J-M. Toxicol. Appl. Pharmacol. 2011.
  
  
• Changes in body composition during breeding: reproductive strategies of three seabird species under poor environmental conditions.
  Jacobs SR, Edwards D, Ringrose J, Elliott KH, Weber J-M, and Gaston AJ. Comp. Biochem. Physiol. B. 2011.
  
  
• Metabolic fuels: Regulating fluxes to select mix.
  Weber J-M. J. Exp. Biol. 2011.
  
  
• Hypoxia stimulates lactate disposal in rainbow trout. 
  Omlin T and Weber J-M.  J. Exp. Biol. 2010.
  
  
• Fuel selection in Wistar rats exposed to cold: shivering thermogenesis diverts fatty acids from reesterification to oxidation.
  Vaillancourt E, Haman F, and Weber J-M.  J. Physiol. (London) 2009.
  
  
• Fatty acid signatures of female Brünnich’s guillemots Uria lomvia suggest reliance on local prey for replacement egg production.
  Jacobs SR, Elliott KH, Gaston AJ, and Weber J-M.  J. Avian Biol. 2009.
  
  
• Mimicking the natural doping of migrant sandpipers in sedentary quails: Effects of dietary n-3 fatty acids on muscle membranes and PPAR expression. 
  Nagahuedi S, Popesku JT, Trudeau VL and Weber J-M.  J. Exp. Biol. 2009.
  See Inside JEB commentary here.
  
  
• The physiology of long-distance migration: Extending the limits of endurance metabolism. 
  Weber J-M.  J. Exp. Biol. 2009.
  
  
• In vivo regulation of rainbow trout lipolysis by catecholamines.
  Magnoni L, Vaillancourt E and Weber J-M.   J. Exp. Biol. 2008.
  
  
• High resting triacylglycerol turnover of rainbow trout exceeds the energy requirements of endurance swimming.  Magnoni L, Vaillancourt E and Weber J-M.  Am. J. Physiol. 2008.
  
  
• Endurance swimming activates trout lipoprotein lipase: Plasma lipids as a fuel for muscle.
  Magnoni L and Weber J-M.  J. Exp. Biol. 2007.
  
  
• Lipid mobilization of long-distance migrant birds in vivo: the high lipolytic rate of ruff sandpipers is not stimulated during shivering.
  Vaillancourt E and Weber J-M. J. Exp. Biol. 2007.
  
  
• Relationship between n-3 PUFA content and energy metabolism in the flight muscle of a migrating shorebird: Evidence for natural doping.
  Maillet D. and Weber J-M.  J. Exp. Biol. 2007.
  
  
• Effects of acute or chronic omega-3 and omega-6 polyunsaturated fatty acid treatment on behavioral, neuroendocrine and cytokine changes elicited by exogenous interleukin-1β challenge. 
  Miguelez M, Anisman H, Weber J-M and Z Merali. J. Neuroimmunol. 2006.
  
  
• Performance-enhancing role of dietary fatty acids in a long-distance migrant: The semipalmated sandpiper.
  Maillet D and Weber J-M.  J. Exp. Biol. 2006.
  
  
• Effects of long-distance migration on circulating lipids of sockeye salmon (Oncorhynchus nerka). 
  Magnoni LJ, Patterson DA, Farrell AP and Weber J-M. Can. J. Fish. Aquat. Sci. 2006.
  
  
• Partitioning oxidative fuels during cold exposure: Muscle glycogen becomes dominant as shivering intensifies.
  Haman F, Péronnet F, Kenny GP, Massicotte D, Lavoie C and Weber J-M. J. Physiol. (London). 2005.
  
  
• Fuel selection in shivering humans.
  Weber J-M and F Haman. Acta Physiologica Scandinavica. 2005.
  
  
• Energetics of a long-distance migrant shorebird (Philomachus pugnax) during cold exposure and running.
  Vaillancourt E, Prud’Homme S, Haman F, Guglielmo CG and Weber J-M.  J. Exp. Biol. 2005.
  
  
• Oxidative fuel selection: adjusting mix and flux to stay alive. Weber J-M and Haman F. In: Animals and Environments, International Congress Series, Elsevier, 2004.
  
  
• Metabolism of normothermic woodchucks during prolonged fasting. 
  Reidy SP and Weber J-M.  J. Exp. Biol. 2004.
  
  
• Fuel selection during intense shivering in humans: EMG pattern reflects carbohydrate oxidation.
  Haman F, Legault SR and Weber J-M.  J. Physiol. (London) 2004.
  
  
• Effects of carbohydrate availability on sustained shivering: I. Oxidation of plasma glucose, muscle glycogen and proteins. 
  Haman F, Péronnet F, Kenny GP, Doucet E, Massicotte D, Lavoie C and Weber J-M.  J. Appl. Physiol. 2004.
  
  
• Effects of carbohydrate availability on sustained shivering: II. Relating muscle recruitment to fuel selection.
  Haman F, Legault SR, Rakobowchuk M, Ducharme MB and Weber J-M.  J. Appl. Physiol. 2004.
  
  
• Fatty acid metabolism in rainbow trout (Oncorhynchus mykiss) tissues: Differential incorporation of palmitate and oleate.
  Weber J-M, Brichon G and Zwingelstein G. Can. J. Fish. Aquat. Sci. 2003.
  
  
• Changes in the fatty acid composition of phospholipids in tissues of farmed sea bass (Dicentrarchus labrax) during an annual cycle.  Roles of environmental temperature and salinity.
  Cordier M, Brichon G, Weber J-M and Zwingelstein G. Comp. Biochem. Physiol. B 2002.
  
  
• Effect of cold exposure on fuel utilization in humans: Plasma glucose, muscle glycogen and lipids.
  Haman F, Péronnet F, Kenny GP, Massicotte D, Lavoie C, Scott C and Weber J-M.   J. Appl. Physiol. 2002.
  
  
• Plasma and muscle phospholipids are involved in the metabolic response to long-distance migration in a shorebird.
  Guglielmo CG, Williams TD, Zwingelstein G, Brichon G and Weber J-M. J. Comp. Physiol. B 2002.
  
  
• Palmitate and oleate metabolism of rainbow trout in vivo.
  Weber J-M, Brichon G, Bodennec J and Zwingelstein G. Comp. Biochem. Physiol. A 2002.
  
  
• Accelerated substrate cycling: a new energy-wasting role for leptin in vivo.
  Reidy SP and Weber J-M. Am. J. Physiol. 2002.
  
  
• Energy cycle in vertebrates: from food to ATP. Weber J-M.  In: Nature Encyclopedia of Life Sciences.
  John Wiley & Sons, Ltd: Chichester. 2001.
  
  
• High-altitude acclimation increases the triacylglycerol / fatty acid cycle at rest and during exercise.
  McClelland GB, Reidy SP, Hochachka PW and Weber J-M. Am. J. Physiol. 2001.
  
  
• Leptin: an essential regulator of lipid metabolism.  
  Reidy SP and Weber J-M. Comp. Biochem. Physiol. A 2000.
  
  
• Energy metabolism of the Virginia opossum during fasting and exercise.
  Weber J-M and O’Connor T.  J. Exp. Biol. 2000.
  
  
• Regulation of glucose production in rainbow trout: role of epinephrine in vivo and in isolated hepatocytes.
  Weber J-M  and Shanghavi DS.   Am. J. Physiol. 2000.
  
  
• Effect of high-altitude acclimation on NEFA turnover and lipid utilization during exercise in rats.
  McClelland GB, Hochachka PW and Weber J-M.  Am. J. Physiol. 1999.
  
  
• Effects of sustained swimming on hepatic glucose production of rainbow trout.
  Shanghavi D and Weber J-M.  J. Exp. Biol. 1999.
  
  
• Glycerol and fatty acid kinetics in rainbow trout: Effects of endurance swimming.
  Bernard SF, Reidy SP, Zwingelstein G and Weber J-M. J. Exp. Biol. 1999.
  
  
• Carbohydrate utilization during exercise after high-altitude acclimation: A new perspective.
  McClelland GB, Hochachka PW and Weber J-M.  Proc. Nat. Acad. Sci. USA. 1998.
  
  
• Adjusting maximal fuel delivery for differences in demand. Weber J-M.  In: Principles of Animal Design: The Optimization and Symmorphosis debate. Cambridge University Press, Cambridge UK, 1998.
  
  
• Effects of hypoxia and low temperature on substrate fluxes in fish: metabolite concentrations are misleading.
  Haman F, Zwingelstein G and Weber J-M. Am. J. Physiol. 1997.
  
  
• Glucose kinetics of the Virginia opossum: Possible implications for predicting glucose turnover in mammals.
  Weber J-M, Fournier R and Grant C.  Comp. Biochem. Physiol. A., 1997.
  
  
• Reliability of continuous tracer infusion for measuring glucose turnover rate in rainbow trout. 
  Haman F, Powell M and Weber J-M. J. Exp. Biol. 1997.
  
  
• Oxidative metabolism in muscle cells. 
  Weber J-M.  In: THE LUNG: Scientific Foundations (2^nd ed.). Lippincott-Raven Publishers, Philadelphia, USA, 1997.
  
  
• Design of the oxygen and substrate pathways:  I. Model and strategy to test symmorphosis in a network structure.
  Taylor CR, Weibel ER, Weber J-M, Vock R, Hoppeler H, Roberts TJ and Brichon G.  J. Exp. Biol. 1996.
  
  
• Design of the oxygen and substrate pathways:  II. Defining the upper limits of carbohydrate and fat oxidation.
  Roberts TJ, Weber J-M, Hoppeler H, Weibel ER and Taylor CR. J. Exp. Biol. 1996.
  
  
• Design of the oxygen and substrate pathways:  III. Partitioning energy provision from carbohydrates.
  Weber J-M, Roberts TJ, Vock R, Weibel ER and Taylor CR.  J. Exp. Biol. 1996.
  
  
• Design of the oxygen and substrate pathways:  IV. Partitioning energy provision from fatty acids.
  Weber J-M, Brichon G, Zwingelstein G, McClelland G, Saucedo C, Weibel ER and Taylor CR.   J. Exp. Biol. 1996.
  
  
• Design of the oxygen and substrate pathways:  V. Structural basis of vascular substrate supply to muscle cells.
  Vock R, Weibel ER, Hoppeler H, Ordway G, Weber J-M and Taylor CR. J. Exp. Biol. 1996.
  
  
• Design of the oxygen and substrate pathways:  VI. Structural basis of intracellular substrate supply to mitochondria in muscle cells. Vock R, Hoppeler H, Claassen H, Wu DXY, Billeter R, Weber J-M, Taylor CR and Weibel ER.   J. Exp. Biol. 1996.
  
  
• Design of the oxygen and substrate pathways:  VII.  Different structural limits for O_­2 and substrate supply to muscle mitochondria. Weibel ER, Taylor CR, Weber J-M, Vock R, Roberts TJ and Hoppeler H.   J. Exp. Biol. 1996.
  
  
• Continuous tracer infusion to measure in vivo metabolite turnover rates in trout.
  Haman F and Weber J-M. J. Exp. Biol. 1996.
  
  
• Effect of endurance training on glycerol kinetics during strenuous exercise in humans.
  Klein S, Weber J-M, Coyle EF and Wolfe RR. Metabolism 1996.
  
  
• Pathways for metabolic fuels and oxygen in high performance fish.
  Weber J-M and Haman F. Comp. Biochem. Physiol. A 1996.
  
  
• Circulatory substrate fluxes and their regulation. Weber J-M and Zwingelstein G. Biochemistry and Molecular Biology of Fishes.  Elsevier Science, Amsterdam, Vol. 4, Metabolic Biochemistry 1995.
  
  
• Lipid composition of tissue and plasma in two Mediterranean fishes, the gilt-head sea bream  (Chrysophrys auratus) and the European sea bass (Dicentrarchus labrax).
  McClelland G, Zwingelstein G, Weber J-M and Brichon G. Can. J. Fish. Aquat. Sci. 1995.
  
  
• Moving cheaply: energetics of walking in the African elephant. Langman VA, Roberts TJ, Black J, Maloiy GMO, Heglund NC, Weber J‑M, Kram R and Taylor CR. J. Exp. Biol. 1995.
  
  
• Effect of exercise on the plasma non-esterified fatty acid composition of dogs and goats: Species with different aerobic capacities and diets. McClelland G, Zwingelstein G, Taylor CR and Weber J-M. Lipids 1995.
  
  
• Locomotory energetics and metabolic fuel reserves of the Virginia opossum.
  Fournier RA and Weber J-M. J. Exp. Biol. 1994.
  
  
• Increased capacity for circulatory fatty acid transport in a highly aerobic mammal. 
  McClelland G, Zwingelstein G, Taylor CR and Weber J-M. Am. J. Physiol. 1994.
  
  
• Alanine kinetics in humans during low-intensity exercise.
  Carraro F, Naldini A, Weber J-M and Wolfe RR. Med. Sci. Sports Exerc. 1994.
  
  
• Mismatch between lipid mobilization and oxidation: glycerol kinetics in running African goats. Weber J-M, Roberts TJ and Taylor CR. Am. J. Physiol. 1993.
  
  
• Pathways for oxidative fuel provision to working muscles: ecological consequences of maximal supply limitations.
  Weber J-M. Experientia 1992.
  
  
• Effect of endurance swimming on the lactate kinetics of rainbow trout.
  Weber J-M. J. Exp. Biol. 1991.
  
  
• Role of the glucose cycle in control of net glucose flux in exercising humans.
  Weber J-M, Klein S and Wolfe RR. J. Appl. Physiol. 1990.
  
  
• Role of the triglyceride-fatty acid cycle in controlling fat metabolism in humans during and after exercise. Wolfe RR, Klein S, Carraro F and Weber J-M. Am. J. Physiol. 1990.
  
  
• Metabolic changes in skeletal muscle and blood of greyhounds during 800-m track sprint.
  Dobson GP, Parkhouse WS, Weber J-M, Stuttard E, Harman JC, Snow DH and Hochachka PW.
  Am. J. Physiol. 1988.
  
  
• Design of exogenous fuel supply systems: Adaptive strategies for endurance locomotion.
  Weber J-M. Can. J. Zool. 1988.
  
  
• L-(+)-lactate translocation into the red blood cells of the skipjack tuna (Katsuwonus pelamis).
  Moon TW, Brill RW, Hochachka PW and Weber J-M. Can. J. Zool. 1987.
  
  
• Cardiac output and oxygen consumption in exercising Thoroughbred horses. Weber J-M, Dobson GP, Parkhouse WS, Wheeldon D, Harman JC, Snow DH and Hochachka PW. Am. J. Physiol. 1987.
  
  
• Lactate kinetics in exercising Thoroughbred horses: Regulation of turnover rate in plasma. Weber J-M, Parkhouse WS, Dobson GP, Harman JC, Snow DH and Hochachka PW. Am. J. Physiol. 1987.
  
  
• Onset of submaximal exercise in thoroughbred horses. Weber J-M, Parkhouse WS, Dobson GP, Harman JC, Snow DH and Hochachka PW. Can. J. Zool. 1987.
  
  
• Mammalian metabolite flux rates in a teleost: lactate and glucose turnover in tuna. Weber J-M, Brill RW and Hochachka PW. Am. J. Physiol. 1986.
  
  
• Effects of hypoxia and surface access on growth, mortality, and behavior of juvenile guppies, Poecilia reticulata. Weber J-M and Kramer DL. Can. J. Fish. Aquat. Sci. 1983.